Complex Systems Biophysics (
) or
Complex systems biology (
) is generally described as a non-reductionist, mathematical theory of emergent living organisms or biosystems in terms of a network, graph
or category
of integrated interactions between their structural and functional components or subsystems. This is often abbreviated to
systems biology
in entries that should be described in fact as complex systems biology.
From a categorical ontology theory of levels viewpoint, however, the term complex is misplaced because systems
with chaos, or chaotic dynamics, are currently defined by physicists as `complex systems', which may have placed a role in the emergence of living systems that are, in fact, super-complex. Therefore, the more appropriate classification of this relatively new area in mathematical or theoretical biology and Biophysics is super-complex systems biology,
-complex systems biology, or simply “systems biology”-as a more general approach where the focus may be not on the super-complexity aspects of living systems but on computer
modeling of physiological, or functional genomics, integration of physiological flows, signaling pathways or interactomics. However, unlike the case of purely functional
-systems theory in abstract relational biology (ARB), complex systems biology (or systems biology) proponents are primarily concerned with the integration of data from a multitude of bioinformatics and genomic/proteomic/post-genomic (primarily structural) data;
scientists also aim to study interactomics or metabolomics primarily through computer-based data analysis, and often Bayesian-based attempts at integration. branches of mathematics that find applications in
are, for example: computer modeling, colored graphs, graph-theoretical based approaches, biotopology, genetic, metabolic and signaling network theories, Bayesian models, biostatistics, correlation techniques, and less frequently: abstract algebra, group
theory, groupoid
and category theory
modeling of cell-cell interactions and biodynamics.
As of this snapshot date, this entry was owned by bci1.